In association with The Society of General Physiologists, The EpIC Seminars are a monthly virtual seminar series, organized by junior faculty and senior postdocs for junior faculty and senior postdocs to showcase some of the most exciting recent research in the field of Electrophysiology and Ion Channels.
Monthly seminars will be held on the 1st Tuesday of the month (see schedule below)
Scroll down for links to recordings of previous seminars
Upcoming events
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The SGP Cranefield Award Seminars
1st December - 12 pm ET / 9 am PT / 5 pm UK / 6 pm CET
Rosa Scala (Washington University in St Louis)
“Muscle fatigue arising intrinsically from SUR2- but not Kir6.1-dependent gain-of-function in Cantu syndrome mice.”
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Sho Horie (Ritsumeikan University)
“A mechanism for pathological oscillations in mouse retinal ganglion cells in a model of night blindness.”
Previous events
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Wojciech Kopec (Queen Mary U of London)
2nd June 2026 - 12 pm ET / 9 am PT / 5 pm UK / 6 pm CET
“Computational electrophysiology of potassium channels”
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Laurie Alice Peverini (U Copenhagen)
5th May 2026 - 12 pm ET / 9 am PT / 5 pm UK / 6 pm CET
“Protein semi-synthesis uncovers NaV1.5 intracellular conformational landscape & regulation”
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Sri Shanmugam (Columbia)
7th April 2026 at 12 pm ET / 9 am PT / 5 pm UK / 6 pm CET
“Engineering cardiac ion channel trafficking: Molecular mechanisms to therapeutic insights”
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Wang Zheng (U Wisconsin - Madison)
3rd March 2026, 12 pm ET / 9 am PT / 5 pm UK / 6 pm CET
Structural and functional basis of mechanosensitive TMEM63 channelopathies
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Stephanie Heusser (Linkoping University)
Tuesday 3rd February, 12 pm ET / 9 am PT / 5 pm UK / 6 pm CET
When things turn sour: How pH controls the molecular mechanisms and pharmacology of acid-sensing ion channels”
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Chris Peters (U Illinois - Chicago)
Tuesday 6th January, 12 pm ET / 9 am PT / 5 pm UK / 6 pm CET
“Neurons and channels of the interpeduncular nucleus underlying nicotine withdrawal”
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Nick Klug (U Vermont)
December 2nd 2025: 12 pm ET / 9 am PT / 5 pm UK / 6 pm CET
“A hypoxic pathway for bladder relaxation: An adenosine receptor/BK channel mechanism”
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Harry Pritchard (University of Manchester)
4th November 2025: 12 - 1 pm ET (9 am PT / 5 pm GMT)
“Mind the Gap: The importance of functional coupling between RyR and BK channels for brain health” -
Elizabeth Akin (University of Nevada, Reno)
Description goes here7th October 2025: 12 - 1 pm ET (9 am PT / 5 pm GMT)
“Building excitable membranes: localization and axonal transport of ion channels and neuropeptides in peripheral neurons”
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Avinash Chandel (UC Santa Barbara)
2nd September 2025: 12 - 1 pm ET (9 am PT / 5 pm GMT)
“Channeling mosquito behavior via TRP channels”
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Olivier Romito (University of Pittsburgh)
5th August 2025: 12 - 1 pm ET (9 am PT / 5 pm GMT)
Role of endothelial Orai1 in IL-1β-induced leukocyte adhesion
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Jake Watson (IST Austria)
1st July 2025: 12 - 1 pm ET (9 am PT / 5 pm GMT)
“A Quest to Explore Hippocampal Micro-circuits, armed with a patch pipette”
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Jia Zhou (UC San Diego)
3rd June 2025: 12 - 1 pm ET (9 am PT / 5 pm GMT)
“Structural Biology of Human GABA-A Receptors from Human Brain Tissue”
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Amanda Lewis (Duke)
6th May 2025: 12 - 1 pm ET (9 am PT / 5 pm GMT)
"Piezo1 ion channels are capable of conformational signaling"
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Sandipan Chowdhury (U Iowa)
1st April 2025: 12 - 1 pm ET (9 am PT / 5 pm GMT)
"𝗣𝗿𝗶𝗻𝗰𝗶𝗽𝗹𝗲𝘀 𝘂𝗻𝗱𝗲𝗿𝗹𝘆𝗶𝗻𝗴 𝗮𝘀𝘀𝗲𝗺𝗯𝗹𝘆 𝗼𝗳 𝗦𝗹𝗼𝟭 𝘄𝗶𝘁𝗵 𝗮𝘂𝘅𝗶𝗹𝗶𝗮𝗿𝘆 𝘀𝘂𝗯𝘂𝗻𝗶𝘁𝘀"
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Ana Isabel Fernandez-Mariño (U Colorado)
4th March 2025: 12 - 1 pm ET (9 am PT / 5 pm GMT)
“Inactivation mechanisms in KV channels”
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Ed Twomey (Johns Hopkins)
4th February 2025: 12 - 1 pm ET (9 am PT / 5 pm GMT)
“Gating and modulation of ionotropic glutamate receptors”
Topic: Ion channel structural biology
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Valeria Kalienkova (U Bergen)
7 Jan 2025: 12 - 1 pm ET (9 am PT / 5 pm GMT)
“A Na+/H+ exchanger with potential”
Topic: Structural biology of membrane transport
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Rían Manville (UC Irvine)
3 Dec 2024 12 pm ET (9 am PT / 5 pm GMT)
“Dynamic regulation of potassium channels: Insights from pharmacology and environmental stimuli”
Topics: KCNQ2/3 channel regulation by endogenous neurotransmitters and ethnobotanicals, and channel-transporter interactions.
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Lisandra Flores-Aldama (U Wisconsin - Madison)
5 Nov 2024: 12 - 1 pm ET (9 am PT / 5 pm GMT)
"The life of hERG1 channels: Mechanisms of gating and biogenesis"
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Tamer Gamal El-Din (U Washington)
1 Oct 2024: 12 - 1 pm ET (9 am PT / 5 pm GMT)
"A tale of two channels causing autism"
Topic: Voltage-gated sodium and calcium ion channels and channelopathies.
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David Jones (U Michigan)
3 Sep 2024: 12 - 1 pm ET (9am PT / 5 pm GMT)
“A hERG1 potassium channel subunit regulates gene expression in developing cardiomyocytes”
Potassium channels and cardiac development
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Anand Saminathan (Harvard)
6th August 2024: 12 - 1 pm ET (9am PT / 5 pm GMT)
“Mechanism of calcium entry in lysosomes”
Endolysosomal transporters
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Emily Caseley (U Leeds)
2 July 2024: 12 - 1 pm ET (9am PT / 5 pm GMT)
KCNT1 channel pharmacology and virtual screening
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Sampurna Chakrabarti (Max Delbrück Center for Molecular Medicine)
4th June 2024: 12 - 1 pm ET (9am PT / 5 pm GMT)
“ Touch sensation requires the mechanically gated ion channel Elkin1.”
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Claudia Moreno (U Washington)
7th May 2024: 12 - 1 pm ET (9 am PT / 5 pm GMT)
Mechanisms of heart rate adaptability
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Fayal Abderemane (UCLA)
2nd April 2024: 12 - 1 pm ET (9 am PT / 5 pm GMT)
How to survive a toxic environment and benefit from it?
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Ashwini Hariharan (U Maryland Baltimore)
5th March 2024: 12 - 1 pm EST (9 am PST / 5 pm GMT)
“Pericyte electro-metabolic signaling controls blood flow in the brain.”
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Ying Yin (Duke)
6th February 2024: 12 - 1 pm ET (9 am PT / 5 pm GMT)
TRPM8 channel structure-function
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Alexandria Miller (U Iowa)
9th January 2023: 12 - 1 pm ET (9 am PT / 5 pm GMT)
Viral ion channels
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Corey Allard (Harvard)
5th December 2023: 12 - 1 pm EST (9 am PST /5 pm GMT)
Evolution, Sensory Biology, Ion Channels, Cephalopods, Structure
“Molecular mechanisms of sensory innovation”
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Leticia Galera-Laporta (UCSD)
7th November 2023: 12 - 1 pm EST (9am PST / 5 pm GMT)
Bacterial ion channels
“New Roles for Ion Channels in Bacteria.”
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Miguel Martín-Aragón Baudel (UC Davis)
3rd October 23 12 - 1 pm EST (9 am PST / 5 pm GMT)
Vascular calcium channels
“Control of vascular Cav1.2 dynamics in pathophysiology”
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Andrew Glazer (Vanderbilt U)
5th September 23 12 -1 pm EST (9 am PST ‘ 5 pm GM)
High-throughput genomics of cardiac arrythmias
“High-throughput mutational studies of cardiac voltage-gated ion channels”
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Swetha Murthy (Vollum)
11th July 23 12 - 1PM EST (9 am PST/5 pm GMT)
Mechanosensitive ion channels
“How do cells sense force and why is it important?”
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Tim Lynagh (U Bergen)
6th June 23 12 - 1PM EST (9 am PST/5 pm GMT)
“A TREEtise on DEG/ENaC and iGluR function”
The Lynagh lab uses molecular phylogenetics to dissect biophysical questions and biophysical experiments to inform our understanding of molecular evolution. In this talk I describe our most recent findings on delta-type ionotropic glutamate receptors and neuropeptide-gated DEG/ENaC channels.
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Willow Coyote-Maestas (UCSF)
2nd May 23 12 - 1PM EST (9 am PST/5 pm GMT)
“Uncovering the secret life of membrane proteins with mechanistic genetic screens.”
Allostery, Protein Engineering, Molecular Evolution, Ion Channels
The SGP-Epic Seminars Organizing Committee
Jelena Baranovic
(University of Edinburgh)
Osama Harraz
(University of Vermont)
Conor McClenaghan
(Rutgers University)
Lejla Zubcevic
(University of Kansas Medical Center)
OUR PARTNERS
The Society of General Physiologists
https://www.sgpweb.org/